Covid-19: What you need to know today. It is important to remember that until the end of 2019 or early 2020, the world did not really know about the presence of the Sars-CoV-2 virus that causes coronavirus infection. Since then, our knowledge of the virus has grown at an unprecedented rate.
Pharma companies, scientists and researchers do not have much luck with medical, new or repetitive drugs. However, they have done this by coming up with a few effective vaccines – and during recording. However, the lack of treatment (so far) means ongoing searches – and a host of traditional, home-made, and experimental treatments are being put in place, not only by those who study at the glittering altar of WhatsApp University, but also by doctors who should know better, and practitioners. lawmakers and administrators who are responsible for not keeping or approving (if only for their peace) a miraculous cure often associated with snake oil.
It is easy to criticize a lawmaker who claims that a normal cow’s urine dose keeps him safe from Covid-19, just as it is a government department that claims that the reintroduced (non-malarial) anti-malarial drug cures Covid -19. But most people are mostly given allopathic drugs. An introduction to how drugs are tested for efficacy and safety may be needed here. They can be tested in silico (or by computer simulation); in vitro (petrol container in the lab); and in vivo (in the human body).
The fact that Covid-19 was a new disease, and the potential for the first wave in other countries (subsequent waves would continue to get worse, but no one knew that back then) led to drug abuse, in some ways it is acceptable to lower the bar for them. For example, it is highly unlikely that only in vitro drugs can be approved for widespread use (even under the authorization of emergency use), but that is exactly what happened with ivermectin (especially in India). This is one of the most effective in vitro drugs (anti-dengue virus, Zika, and yellow fever, among other diseases), but it fails to replicate in vivo (there can be countless reasons for this, including the body’s ability to absorb the drug). Think of it as a Ranji Trophy player presses Test cricket (and tomorrow’s wet and windy Trent Bridge). Unfortunately, subsequent in vivo studies have shown that vermectin does not appear to help a person with Covid-19 infection. The same is true of Favipiravir, Itolizumab, Doxycycline, and even 2-DG.
Well-conducted clinical trials may prove that some of them are indeed effective, but the available scientific evidence (and I use this term with caution, because in this age of certain facts, there is also some scientific evidence) does not justify the interest given to these drugs, and they are consumed. Worse still, drug lords around the world (and in India) are very quick (and worst of all, inconsistent) in their acceptance of treatment, even if they use it for emergencies.
There is usually a price to pay for drug abuse, even if this is not immediate. One study has shown that there is a link between the use of recovery plasma – the Indian Medical Research Council finally removed it from the treatment process on May 17 – and the mutation of the Sars-CoV-2 virus (more research is needed before this can be firmly established, however). And many doctors believe (as I do) that there is a clear link between the overuse of steroids in the treatment of Covid and the growing incidence of mucormycosis, or black fungus.
The damage caused by Covid-19 is significant, but it can be tragic if, in our emergency of finding a better cause for coronavirus, the drug – and the evidence is in jeopardy.
There has been a lot of talk about the third Covid-19 wave in India that affects children more than any other segment of the population. It is important to point out that this is a standardized test. Since it is unlikely that children (those under the age of 18) will be vaccinated during the third wave, it is clear that they are as vulnerable as any other non-vaccinated group. And there are no data or studies suggesting that children are at risk of SARS-CoV-2 virus-induced Covid-19 infection, or vice versa, than ever before (therefore, less children are less likely to die from Covid-19, or even need hospitalization remains a reality). That means, it makes sense to vaccinate them, and it’s early.