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After two reactions, UK says that those with allergies should not get Pfizer vaccine.

The UK’s first Covid-19 vaccine came out. It was hailed by Britain on Tuesday this week. And this day was known as “V-Day” —It hit serious problems within 24 hours after someone with a serious allergy to vaccines, medicines or any kind of food was told not to take the Pfizer vaccine.


The Medicines and Healthcare Products Regulatory Agency told on Wednesday a new advice across the country saying that any person having a history of any kind of allergic reaction to a vaccine, any medicine or some particular food in previous history of any anaphylactoid reaction or those who have been advised to carry an adrenaline autoinjector should not receive or take the Pfizer BioNtech vaccine.

They advised that, resuscitation facilities should be available all the times for all vaccinations. Vaccination should only be carried out where resuscitation measures are available.

However some experts advised the people and told them not to panic. Stephen Evans who is the professor at the London School of Hygiene & Tropical Medicine, said that it was not unexpected. He also added that for the general population this does not mean that they need to be anxious or worried about receiving the vaccination. He said that an individual has to remember that even things like Marmite can cause unexpected allergic reactions.

The MHRA statement came after two of the NHS workers reported that they had suffered allergic reactions on Tuesday after taking the Pfizer BioNtech Covid-19 vaccine. Both suffered anaphylactoid reactions, In which skin rash can involve, nausea and also vomiting. Both of them have a strong past history of allergic reactions and also carried an adrenaline auto injector.

After two reactions, UK says that those with allergies should not get Pfizer vaccine.
After two reactions, UK says that those with allergies should not get Pfizer vaccine.


The MHRA said the staff developed symptoms shortly after receiving the vaccine of COVID. Both recovered after appropriate treatment. An MHRA spokesperson told that they are fully investigating the two reports that have been reported to them as a matter of priority. Once all the information has been reviewed, they will communicate updated advices. In line with existing advice, they advise anyone with a history of a significant allergic reaction due to receive the Pfizer Covid vaccine to speak to their healthcare professional who are administering the vaccine.

 
Several different people were vaccinated in the hospital clinics on the first day when UK started giving the vaccine. A Pfizer spokesperson said that they have been advised by MHRA. The MHRA told about the two yellow card reports that can be associated with allergic reaction because of the Covid-19 BNT162b2 vaccine.

Pfizer and BioNTech are the ones who are supporting the MHRA in the investigation for the same. In the Phase 3 clinical trial, this vaccine was generally well and also it did not have any serious safety concerns reported by the independent data monitoring committee. The trial has enrolled over 44,000 participants and over 42,000 of whom have received a second vaccination.


Professor Stephen Powis who is the director for the NHS, said that it is common with new vaccines the MHRA have advised that people with a history of allergic reactions should not receive this vaccination. The two people who responded adversely to the vaccine because of the allergy are recovering well.

Stephen Evans of the London School of Hygiene & Tropical Medicine said that Allergic reaction occurs with quite a number of vaccines, and perhaps even more frequently with the drugs… The Pfizer data showed that about 0.6% of people had some form of allergic reactions and that was found in the trial on the vaccine. So there was an of course excess of allergic reaction but this was small and the true rate is not known yet.


Peter Openshaw who is a professor of experimental medicine at the Imperial College London said the fact that they know so soon about these two allergic reactions, and that the regulator has acted on this to issue precautionary advice and this shows that monitoring system is working well.

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